1. Monro-Kellie Doctrine - Pathophysiology - Herniation
The Monro-Kellie Doctrine was first described by Dr Alexander Monro and Dr George Kellie. It describes the relationship between the contents of the cranium ...
The Monro-Kellie Doctrine was first described by Dr Alexander Monro and Dr George Kellie. It describes the relationship between the contents of the cranium and intracranial pressure.
2. Monro-Kellie 2.0: The dynamic vascular and venous ...
This article reviews the Monro-Kellie doctrine, categorises venous outflow limitation conditions, relates physiological mechanisms to clinical conditions
For 200 years, the ‘closed box’ analogy of intracranial pressure (ICP) has underpinned neurosurgery and neuro-critical care. Cushing conceptualised the Monro-Kellie doctrine stating that a change in blood, brain or CSF volume resulted in reciprocal ...
3. Monro-Kellie Doctrine: A Brief Review | NursingCenter
13 jan 2023 · The Monro-Kellie doctrine describes the direct relationship between the contents of the cranium and intracranial pressure. Learn more here.
Jan 13 2023 by Jennifer Collins, MSN, AGACNP-BC
4. The Monro-Kellie Doctrine: A Review and Call for Revision
1 dec 2022 · The Monro-Kellie doctrine is a well-accepted principle of intracranial hemodynamics. It has undergone few consequential revisions since it was established.
SUMMARY: The Monro-Kellie doctrine is a well-accepted principle of intracranial hemodynamics. It has undergone few consequential revisions since it was established. Its principle is straightforward: The combined volume of neuronal tissue, blood, and CSF is constant. To maintain homeostatic intracranial pressure, any increase or decrease in one of these elements leads to a reciprocal and opposite change in the others. The Monro-Kellie doctrine assumes a rigid, unadaptable calvaria. Recent studies have disproven this assumption. The skull expands and grows in response to pathologic changes in intracranial pressure. In this review, we outline what is known about calvarial changes in the setting of pressure dysregulation and suggest a revision to the Monro-Kellie doctrine that includes an adaptable skull as a fourth component. IIH : idiopathic intracranial hypertension SIH : spontaneous intracranial hypotension
5. Continuous Monitoring of the Monro-Kellie Doctrine: Is It Possible?
We propose that the Monro-Kellie doctrine can be monitored in real time to illustrate the state of intracranial volume regulation.
The Monro-Kellie doctrine describes the principle of homeostatic intracerebral volume regulation, which stipulates that the total volume of the parenchyma, cerebrospinal fluid, and blood remains constant. Hypothetically, a slow shift (e.g., brain ...
6. [PDF] Monro-Kellie 2.0: The dynamic vascular and venous ... - CORE
While the traditional Monroe-Kellie doctrine holds, imbalances in arterial inflow and venous outflow also affect ICP. The venous outflow can be altered intracra ...
7. An update to the Monro–Kellie doctrine to reflect tissue compliance ...
16 dec 2020 · An update to the Monro–Kellie doctrine to reflect tissue compliance after severe ischemic and hemorrhagic stroke.
High intracranial pressure (ICP) can impede cerebral blood flow resulting in secondary injury or death following severe stroke. Compensatory mechanisms include reduced cerebral blood and cerebrospinal fluid volumes, but these often fail to prevent raised ICP. Serendipitous observations in intracerebral hemorrhage (ICH) suggest that neurons far removed from a hematoma may shrink as an ICP compliance mechanism. Here, we sought to critically test this observation. We tracked the timing of distal tissue shrinkage (e.g. CA1) after collagenase-induced striatal ICH in rat; cell volume and density alterations (42% volume reduction, 34% density increase; p < 0.0001) were highest day one post-stroke, and rebounded over a week across brain regions. Similar effects were seen in the filament model of middle cerebral artery occlusion (22% volume reduction, 22% density increase; p ≤ 0.007), but not with the Vannucci-Rice model of hypoxic-ischemic encephalopathy (2.5% volume increase, 14% density increase; p ≥ 0.05). Concerningly, this ‘tissue compliance’ appears to cause sub-lethal damage, as revealed by electron microscopy after ICH. Our data challenge the long-held assumption that ‘healthy’ brain tissue outside the injured area maintains its volume. Given the magnitude of these effects, we posit that ‘tissue compliance’ is an important mechanism invoked after severe strokes.
8. Trinasia Kelly - Softball - Monroe University Athletics
Position: OF. Height: 5-5. Class: Sophomore. Highschool: Frederick Douglass Academy. Hometown: New York, NY. Summary; Media; Season; Career; Historical ...
Trinasia Kelly (7) OF
9. The State of Spontaneous Intracranial Hypotension in 2020: A Mini-Review
31 dec 2020 · The classic Monroe-Kelly doctrine was established in the late 1700s to early 1800s8,9, describing a constant volume of blood, brain and CSF ...
The history of intracranial hypotension dates back to the early 1900’s, when trephined patients with depressed scars were observed to show decreased pressures via lumbar puncture manometry.
10. Anton Kelly - Monroe Community College Athletics
Height: 5-11 · Year: So. · Hometown: Motherwell, Scotland · High School: Our Lady's HS · Position: Defense.
Anton Kelly
